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Overcome Male Infertility – What is Biochemical Analysis?
As we mentioned in previous articles, infertility is defined as the inability of a couple to conceive after 12 months of unprotected sex. It affects more than 5 million couples in the United States and many more around the world. Due to lack of knowledge of treatments, only 10% seek help from a professional specialist. In this article, we will discuss what is biochemical analysis for male infertility?
I. Definition
The study of chemicals and vital processes occurring in the male testicle, such as white blood cell concentration, semen fructose level, ejaculate volume, pH, and liquefaction time.
II. Procedure
The semen sample of semen is collected at the clinic laboratory by masturbation, the semen is sent for analysis of chemical substances and vital processes as mentioned in the definition.
III. Diagnostic
This test usually performs a semen analysis for
1.Volume
The semen sample required for this test is not less than 2.0ml or more
It measures the number of sperm cells per milliliter (ml) of ejaculate
2. pH
pH is a measure of the acidity or basicity of a solution (a pH of 07 is considered neutral). In this test, it takes between 7.2 and 8.0 to be considered normal.
3. Sperm Concentration
It measures the number of spermatozoa per milliliter of ejaculate, for a normal concentration of spermatozoa it takes 20,000,000 per ml or more.
4. Motility
Motility is a measure of sperm movement, normal sperm motility is 50% or more with forward progression. It can be classified in 4 grade
a) Sperm with progressive motility:
They are the strongest and they swim fast in a straight line
b) Nonlinear Motility: These also move forward but tend to move in a curved or twisted motion.
c) Non-progressive motility:
The sperm do not move forward despite moving their tails.
d) Non motility:
Do not move at all.
5. Rapid forward progressive motility
The semen sample must contain at least 25% or more of this type of sperm to be considered normal.
6. Morphology
It is the study of the normal and abnormal shape of sperm. It is considered normal if it is
a) 30% or more normal forms (WHO criteria)
b) 11% or more normal forms (strict Tygerberg criteria developed by Dr Roelof Menkveld, Tygerberg Hospital, South Africa, and disseminated by Dr Thinus Kruger)
7. Vitality
The sample must contain at least 75% live sperm in a semen sample
8. White blood cells
The sample must have a white blood cell count of less than 1,000,000 per ml. Otherwise, it may be an indication of immune causes of infertility and more testicles are needed.
Sometimes the semen sample may also be tested for gallbladder function, citrate or acid phosphatase for the prostate, and free carnitine as an index of epididymal function, if requested by your fertilization specialist.
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